Assistant Professor

Department of Pharmaceutical Sciences
College of Pharmacy
Larkin University

Contact Information

Office: TBA
Office Phone: 305-760-7486

Email: nlounsbury@ULarkin.org
Office Hours: TBA

Education and Training

B.S. Chemistry

Worcester Polytechnic Institute

Worcester, Massachusetts

Ph.D.

Medicinal Chemistry

Temple University

Philadelphia, Pennsylvania

Teaching Interests

Dr. Lounsbury’s teaching interest includes various Pharm.D. courses, such as Medicinal Chemistry, Pharmaceutical Chemistry and Pharmaceutical Compounding.

Scholarly Interests

Dr. Lounsbury’s research interests are in the discovery and development of novel pharmaceuticals. Her academic research experience was focused on the design of novel antimicrobials for methicillin-resistant S. aureus and chalcone activators of Nrf2. Her research interests also include the development of inhibitors of CXCR7 for the treatment of lung cancer.

Selected Recent Publications

Kurimchak AM, Shelton C, Duncan KE, Johnson KJ, Brown J, O’Brien S, Gabbasov R, Fink LS, Li Y, Lounsbury N, Abou-Gharbia M, Childers WE, Connolly DC, Chernoff J, Peterson JR, Duncan JS. Resistance to BET bromodomain inhibitors is mediated by kinome reprogramming in ovarian cancer. Cell Reports 16: 1273-1286 (2016)

Lounsbury N, Mateo G, Jones B, Papaiahgari S, Thimmulappa RK, Teijaro C, Gordon J, Korzekwa K, Ye M, Allaway G, Abou-Gharbia M, Biswal S, Childers W. Heterocyclic chalcone activators of nuclear factor (eryhtoid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy. Bioorganic and Medicinal Chemistry 23: 5352-5359 (2015)

Eidem, TM, Lounsbury N, Emery JF, Bulger J, Smith A, Abou-Gharbia M, Childers W, Dunman PM. Small molecule inhibitors of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing. Antimicrobial Agents and Chemotherapy 59: 2016-2028 (2015)

Publication list via PubMed:

http://www.ncbi.nlm.nih.gov/pubmed/?term=nicole+lounsbury

Selected Recent Presentations

Lounsbury N, Eidem T, Mateo G, Dunman PM, Childers W. Novel inhibitors of Staphylococcus aureus RnpA. American Association of Pharmaceutical Scientists Annual Meeting, Orlando, FL, October 25- 29, 2015.

Lounsbury N, Mateo G, Jones B, Papaiahgari S, Thimmulappa RK, Teijaro C, Gordon J, Korzekwa K, Ye M, Allaway G, Abou-Gharbia M, Biswal S, Childers W. Heterocyclic chalcone Nrf2 activators with improved bioavailability. Philadelphia Organic Chemistry Club Poster Session, Philadelphia, PA, May 26, 2015.

Lounsbury N, Fan R, Blass B, Childers W, Abou-Gharbia M, Sattler R. Synthesis and evaluation of harmine analogs as enhancers of glutamate uptake. Philadelphia Pharmaceutical Forum Student Poster Session, Philadelphia, PA, March 14, 2013.

Awards and Honors

Ronald Gautieri Scholarship Fund Award, Temple University, 2016.

Rho Chi Honor Society, Temple University.